Found 10 matching trials
A Study of a Retroviral Replicating Vector Combined With a Prodrug Administered to Patients With Recurrent Malignant Glioma PHASE1 This is a multicenter, open-label, ascending-dose trial of the safety and t...
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A Study of Toca 511 & Toca FC in Patients With Recurrent High Grade Non-Muscle Invasive Bladder Cancer (Toca 8) PHASE1 This is a Phase 1, multicenter, open-label study of intravesical Toca 511 f...
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Multiple Locations
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The Toca 5 Trial: Toca 511 & Toca FC Versus Standard of Care in Patients With Recurrent High Grade Glioma PHASE2 This is a multicenter, randomized, open-label phase 2/3 study of Toca 511 a...
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Barrow Neurological Institute at Dignity Health St. Joseph's Hospital and Medical Center
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A Study of the Safety of Toca 511, a Retroviral Replicating Vector, Combined With Toca FC in Subjects With Newly Diagnosed High Grade Glioma Receiving Standard of Care PHASE1 This is a multi-center, open label trial of combination therapy with Toca 5...
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Multiple Locations
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A Continuation Protocol for Patients Previously Enrolled in a Study of Toca 511 PHASE1 This is a multicenter, open-label, continuation study to allow subjects who...
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University of California, Los Angeles
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A Study of Toca 511, a Retroviral Replicating Vector, Combined With Toca FC in Patients With Solid Tumors or Lymphoma (Toca 6) PHASE1 The purpose of this trial is to evaluate changes in immune activity relativ...
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Sarah Cannon Research Institute
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Study of a Retroviral Replicating Vector Given Intravenously to Patients Undergoing Surgery for Recurrent Brain Tumor PHASE1 This is a multicenter study evaluating the safety and tolerability of Toca ...
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DB107-RRV, DB107-FC, and Radiation Therapy With or Without Temozolomide (TMZ) for High Grade Glioma PHASE1 This is a multicenter, open-label study of DB107-RRV (formerly Toca 511) an...
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University of Southern California
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Study of a Retroviral Replicating Vector Combined With a Prodrug to Treat Patients Undergoing Surgery for a Recurrent Malignant Brain Tumor PHASE1 This is a multicenter study evaluating the safety and tolerability of incre...
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Testing the Addition of an Anti-cancer Viral Gene Therapy, Toca 511/Toca FC, to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed Glioblastoma PHASE2 This phase II/III trial studies how well vocimagene amiretrorepvec (Toca 51...
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Multiple Locations
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